Hotels in Medical Center District

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Medical Center District hotels that make comfort easy

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our prices for Medical Center District are cheapest in January

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Price trends for hotels in Medical Center District
Pricing is based on two traveler single night rates
View properties in September
Currently viewing crowd sizes and weather for September.
Weather forecast for San Antonio
September
trending_downLow crowds
High 91°F / low 73°F. Sunny most days.
View properties in September
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September, Low crowds, average high temperature 91 degrees Fahrenheit, average low temperature 73 degrees Fahrenheit. Sunny most days.
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October, High crowds, average high temperature 83 degrees Fahrenheit, average low temperature 64 degrees Fahrenheit. Sunny most days.
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November, Low crowds, average high temperature 71 degrees Fahrenheit, average low temperature 54 degrees Fahrenheit. Sunny most days.
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December, High crowds, average high temperature 65 degrees Fahrenheit, average low temperature 48 degrees Fahrenheit. Sunny most days.
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January, Low crowds, average high temperature 63 degrees Fahrenheit, average low temperature 45 degrees Fahrenheit. Sunny most days.
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February, Low crowds, average high temperature 66 degrees Fahrenheit, average low temperature 48 degrees Fahrenheit. Sunny most days.
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March, High crowds, average high temperature 74 degrees Fahrenheit, average low temperature 55 degrees Fahrenheit. Sunny most days.
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April, Moderate crowds, average high temperature 81 degrees Fahrenheit, average low temperature 61 degrees Fahrenheit. Sunny most days.
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May, Moderate crowds, average high temperature 86 degrees Fahrenheit, average low temperature 68 degrees Fahrenheit. Sunny most days.
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June, Moderate crowds, average high temperature 93 degrees Fahrenheit, average low temperature 73 degrees Fahrenheit. Sunny most days.
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July, High crowds, average high temperature 96 degrees Fahrenheit, average low temperature 76 degrees Fahrenheit. Sunny most days.
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August, Moderate crowds, average high temperature 97 degrees Fahrenheit, average low temperature 77 degrees Fahrenheit. Sunny most days.
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Monthly weather averages (˚F)

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Check out reviews of Medical Center District hotels guests love

Frequently asked questions

Is Medical Center District expensive to stay in?
You can find great hotels from $51 in Medical Center District to suit a range of budgets. If you're looking for an affordable stay in Medical Center District, La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW and Clarion Pointe near Medical Center are some great low-cost options. To find the best low-cost hotel on Hotels.com that meets your needs, apply your search filters and then sort hotels by "Price: low to high".
How can I find discounted rates and deals for Medical Center District hotels?
Unlocking discounted rates at hotels in Medical Center District couldn't be simpler. Members save up to 20% on select hotels when signed in. Silver, Gold, and Platinum members can earn additional rewards on VIP Access bookings.
Can I receive a refund if I cancel my Medical Center District hotel booking?
The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel your booking. Some Medical Center District hotels require you to cancel more than 24 hours before check-in, so look at your booking beforehand. For extra peace of mind before you book, filter hotels by "Property cancellation options" and select "Fully refundable property".
What are some of the best pet-friendly hotels in Medical Center District?
Traveling with your pet doesn't mean sacrificing a great hotel stay. In Medical Center District, our travelers love:
What are some of the best Medical Center District hotels for couples?
One of the best Medical Center District hotels for couples is San Antonio Marriott Northwest Medical Center. San Antonio Marriott Northwest Medical Center is a popular hotel with a restaurant, as well as champagne service in each guestroom. Travelers also love La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW where you can enjoy an outdoor pool. Find more romantic Medical Center District hotels by using the "Traveler experience" filter in your search and selecting "Adults only" or "Romantic".
What are some of the best family hotels in Medical Center District?
If you're vacationing with your family, Courtyard by Marriott Medical Center San Antonio and La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW are some of the best family hotels in Medical Center District. Courtyard by Marriott Medical Center San Antonio has a great average guest score of 8.8 out of 10 and amenities like an outdoor pool, children's meals and in-room cribs. Kids are welcome at La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW, too. Travelers leave glowing reviews of this hotel, which has an outdoor pool, a hot tub, in-room cribs, and more. To explore more family hotels in Medical Center District, use the "Family friendly" filter in your search on Hotels.com.
What are some of the best Medical Center District hotels with a pool?
Book a Medical Center District hotel with a pool for some added relaxation or exercise on your trip. Drury Inn & Suites San Antonio Northwest Medical Center is a top-rated hotel with an indoor pool, and an average guest score of 9.2 out of 10. This hotel also features a hot tub and a free buffet breakfast. Courtyard by Marriott Medical Center San Antonio is another great hotel that features an outdoor pool, along with a restaurant and a bar/lounge. For more Medical Center District hotels with a pool, use the "Amenities" filter in your search and select "Pool" on Hotels.com.
What are some of the top Medical Center District hotels with free parking?
If you're traveling by car, make your life easier by booking a Medical Center District hotel with free parking. Our travelers like:
Is it worth staying in Medical Center District?
You're spoilt for choice with 121 hotels in the area so it's easy to find your perfect somewhere. Basing yourself in Medical Center District makes it easy to explore San Antonio, including the neighborhoods of Far West Side and Uptown.
What are some great hotels in Medical Center District with balconies?
There are some top hotels in Medical Center District that offer rooms with a balcony. Check out San Antonio Marriott Northwest Medical Center which has a high guest score of 8.6 out of 10, and balconies in some rooms. Another popular choice is Courtyard by Marriott Medical Center San Antonio, which offers balconies in some rooms and has a great guest score of 8.8.
Are all taxes and fees included in the Medical Center District hotel prices shown on Hotels.com?
Hotels.com provides upfront pricing so you can relax knowing you won't be met with surprise additional fees or taxes when you're ready to confirm your booking. From the time you start your search on Hotels.com, the price you see is what you pay. This makes it much easier to compare properties and secure our best deal for your next getaway.

Find out more about Medical Center District

Find out more about Medical Center District

Explore the Vibrant Heartbeat of Innovation and Adventure in the Medical Center District

Discover the Medical Center District in San Antonio, Texas, a vibrant hub where healthcare innovation meets urban charm. This dynamic area is home to renowned medical institutions, offering cutting-edge health services and educational opportunities. Beyond its medical prowess, explore nearby attractions like the picturesque San Antonio Botanical Garden, indulge in local cuisine at charming eateries, or catch a game at the nearby stadium. With convenient access to downtown San Antonio's rich cultural scene, the Medical Center District is an intriguing blend of modernity and tradition, perfect for both health-focused travelers and urban explorers alike.

Discover great hotels in Medical Center District

The Medical Center District in San Antonio offers a variety of comfortable accommodations, catering to diverse travelers. Guests can find friendly hotels with well-appointed guest rooms, making it a convenient base for exploring the city while enjoying quality service and amenities. These are some of the hotels preferred by our travelers in Medical Center District:

  1. Motel 6 San AntonioOpens in a new window: This inviting 2.0-star motel offers a comfortable stay for travelers seeking a pet-friendly experience. Guests appreciate the warm ambiance and the convenience of onsite pet accommodations, making it a delightful choice for those traveling with furry companions. The property boasts a welcoming atmosphere, ideal for a relaxed vacation, and has garnered positive sentiments for its affordability and basic comforts.
  2. Howard Johnson by Wyndham San Antonio/NW Medical CenterOpens in a new window: Howard Johnson by Wyndham San Antonio/NW Medical Center is a sophisticated 3.0-star hotel designed for business travelers. With multiple meeting rooms and a 24-hour business center, it provides a seamless experience for those on the go. The property stands out for its modern design and efficient services, ensuring that busy professionals can focus on their work while enjoying a pleasant stay. Positive reviews highlight its strategic location and thoughtful amenities, making it a preferred choice for corporate journeys.
  3. The Westin San Antonio NorthOpens in a new window: As a luxurious 4.0-star hotel, The Westin San Antonio North caters to discerning travelers seeking a blend of business and leisure. With a 24-hour business center, conference space, and a stunning architectural design, it creates an upscale environment for professionals. The property also features family-friendly amenities, ensuring a comfortable stay for those traveling with children. Guests have expressed appreciation for its elegant atmosphere and top-tier services, making it a standout choice for high-quality experiences.

Top locations to stay in Medical Center District

Staying near Six Flags Fiesta Texas, University of Texas at San Antonio, and University of Texas Health and Science Center at San Antonio offers diverse attractions. Six Flags provides thrilling rides, UTSA boasts educational and cultural experiences, and the Health Science Center is a hub for medical innovation. For first-time visitors, staying near Six Flags Fiesta Texas is ideal for entertainment and fun.

  1. Near Six Flags Fiesta TexasOpens in a new window: Staying near Six Flags Fiesta Texas means you’re just a stone's throw away from exhilarating rides and family-friendly attractions. The area also boasts great shopping at The Shops of La Cantera and The Rim Shopping Center, where you can find a variety of stores and dining options. For a cultural experience, catch a performance at nearby theaters like the Sheldon Vexler Theatre, making it a well-rounded spot for fun and entertainment.
  2. Near University of Texas at San AntonioOpens in a new window: When you stay near the University of Texas at San Antonio, you’re in a vibrant area full of energy. Enjoy access to outdoor activities at the nearby Palmer Course at La Cantera and explore the scenic landscapes. The location offers diverse shopping opportunities at Huebner Oaks, along with cultural attractions such as Cinemark San Antonio 16 for movie nights, ensuring there’s always something to do.
  3. Near University of Texas Health and Science Center at San AntonioOpens in a new window: Choosing to stay near the University of Texas Health and Science Center at San Antonio puts you in a thriving community with a focus on wellness and health. You can enjoy the tranquility of parks and recreational areas, while also having easy access to cultural attractions in the vicinity. Additionally, the area's shopping centers provide convenience for any last-minute needs during your stay.

Things to do near Medical Center District

The Medical Center District offers a vibrant mix of modern amenities and natural beauty. Explore lush parks, enjoy outdoor activities like hiking and boating, or unwind at nearby beaches. With shopping centers and entertainment venues around, it’s a lively hub perfect for a fun-filled getaway. Plus, convenient accommodations make it easy to relax after a day of exploration!

  • River WalkOpens in a new window – Stroll along this scenic esplanade, lined with vibrant shops, delightful eateries, and picturesque views of the San Antonio River. Enjoy a leisurely boat ride or simply soak in the lively atmosphere as you explore the charming bridges and lush landscapes that make this area a beloved highlight of the city.
  • Six Flags Fiesta TexasOpens in a new window – Thrill-seekers will love this expansive theme park, offering a variety of roller coasters, water rides, and family-friendly attractions. Dive into a day filled with excitement, from adrenaline-pumping rides to entertaining shows. Make sure to grab some tasty snacks as you wander through the colorful park, designed for fun at every turn.
  • San Antonio SeaWorldOpens in a new window – Experience the wonders of the ocean at this thrilling theme park, where you can see awe-inspiring marine life and enjoy exhilarating rides. Engage with lively shows featuring dolphins and sea lions, and don’t miss the chance to cool off at the water attractions. It’s a perfect spot for families looking to combine education with entertainment.

5 tips for savvy savings when booking a hotel in Medical Center District

  1. Book for the cheapest times: The most budget-friendly months to visit the Medical Center District are January, September, and November when hotel prices tend to be lower. To fully experience the area's historic landmarks, cultural sites, and natural attractions, a stay of at least 2 to 3 days is recommended. Visitors can explore significant locations like historic buildings, national parks, art museums, and recreational areas, all offering great value for money. With the possibility of prices dropping during these months, this is an ideal time for those traveling on a budget to enjoy the rich history and culture the Medical Center District has to offer.
  2. Look for last-minute deals on Hotels.com: To explore last-minute deals in the Medical Center District, start by checking the DealsOpens in a new window or Last-Minute DealsOpens in a new window sections on Hotels.com, where you may discover discounted hotel rates as your travel date approaches. You could also enable email alerts or push notifications to stay updated on flash sales and exclusive promotions, helping you seize opportunities to save. Additionally, Smart ShoppingOpens in a new window is a comparison tool available in the app that allows you to compare hotel prices and amenities, ensuring you're more likely to see the best options available.
  3. Be flexible with dates: Prices can fluctuate depending on factors like the hotel's location, star rating, and the time of year, so being flexible with your travel dates may help you save on your stay in the Medical Center District. For those seeking a unique experience, boutique hotels often provide a more personalized touch and sometimes offer better value. When you book with Hotels.com, we'll inform you if the price for your chosen dates is above or below the average. If the price is on the higher end, we’ll suggest alternative dates that could be more affordable, helping you find a better deal.
  4. Consider your location: Choosing accommodations near major attractions or downtown areas can be convenient, but it often tends to come with a higher price tag. For better rates, you might want to look at hotels in less central neighborhoods, striking a balance between cost and accessibility to your desired destinations. Additionally, consider independent hotels located a bit farther out; they are often more likely to be affordable and can offer a more genuine experience.
  5. Become a Member: Join our membership for free and start planning your next stay in the Medical Center District! Enjoy exclusive member prices and save on over 100,000 hotels around the globe. As a member, you'll have the opportunity to advance through tiers, unlocking exciting perks such as complimentary room upgrades (when available) and discounts on food and beverages at select VIP Access properties. Don’t miss out on these fantastic benefits—sign up today!

Best time to go to Medical Center District

Medical Center District has a varied climate due to its size, so the best time to visit depends on the region and your preferences for weather and crowds. If you’re looking to soak up the lively atmosphere in Medical Center District, March, June, and July are the peak months to visit, bustling with fellow travelers. During this peak period, the weather is mostly sunny, with light rainfall. However, if you prefer a more relaxed experience, January, February, and September are perfect for a quieter getaway, marked by no to light rainfall and mostly sunny conditions.

What's Medical Center District Like?

If you're in search of the perfect part of the city to explore, look no further than Medical Center District. Take time to see places like USAA Corporate Office Headquarters and Cinemark San Antonio 16 while you're here. Popular sights worth seeing in the larger area include Six Flags Fiesta Texas and Lackland Air Force Base.

How to Get to Medical Center District

Flying to:

  • San Antonio International Airport (SAT), 6.4 mi (10.3 km) from Medical Center District

Things to See and Do in and around Medical Center District

Things to See near Medical Center District:

  • USAA Corporate Office Headquarters (2.3 mi/3.8 km away)
  • St. Mary's University (3.7 mi/6 km away)
  • Bandera Road Community Church (4.3 mi/7 km away)
  • Blessed Sacrament Catholic Church (4.8 mi/7.7 km away)
  • First Unitarian Universalist Church (1.8 mi/2.9 km away)

Things to Do near Medical Center District:

  • The San Antonio Art Institute (2 mi/3.2 km away)
  • Huebner Oaks (3 mi/4.8 km away)
  • Ingram Park Mall (3.7 mi/5.9 km away)
  • North Star Mall (5 mi/8 km away)
  • Wonderland of the Americas Mall (1.8 mi/2.9 km away)

When Is the Best Time to Visit San Antonio?

  • Hottest months: August, July, June, September (average 84°F)
  • Coldest months: January, February, December, November (average 57°F)
  • Rainiest months: May, September, April, October (average 4 inches of rainfall)

Medical Center District Travel Information

Best Time to Visit
March, October and December
Average Stay
2 days
Closest Neighborhoods
Downtown San Antonio, Alamo Plaza
Top Attractions
San Antonio Aquarium, University of Texas Health and Science Center at San Antonio, Huebner Oaks

Keep exploring

Keep exploring