Comfort Inn & Suites Santee

Santee hotel in entertainment district

Choose dates to view prices

Where to?

Dates

October 2025

25

November 2025

Frette Italian sheets, premium bedding, pillowtop beds, blackout drapes

In the heart of the entertainment district, Comfort Inn & Suites Santee offers a warm welcome with a free breakfast buffet and cozy fireplace in the lobby. Stay active at the gym, get work done at the business center, or unwind by seasonal outdoor pool. With laundry facilities and helpful staff on site, this hotel has everything you need for an enjoyable stay.

Very good

Popular amenities

Pool
Connecting rooms available
Gym
Laundry facilities
24/7 front desk
Air conditioning

Main amenities (12)

Daily housekeeping
Fitness center
Seasonal outdoor pool
Business center
24-hour front desk
Coffee/tea in a common area
Computer station
Lobby fireplace
Front-desk safe
Vending machine
Water dispenser
Self-serve laundry

For families (6)

Children stay free
Free cribs/infant beds
Connecting/adjoining rooms available
Private bathroom
Television
Daily housekeeping

$101 nightly

Nov 2 - Nov 3

Total with taxes and fees

Room options

Check availability for these dates

Tonight

Oct 25 - Oct 26

Tomorrow

Oct 26 - Oct 27

All rooms

1 bed

2 beds

3+ beds

Showing 10 of 10 rooms

Standard Room, 1 King Bed

Wonderful

Highlights

Air conditioning

Connecting rooms available

Free cribs/infant beds

Plasma TV

Renovated in 2023

Frette Italian linens

Blackout drapes/curtains

Pillowtop bed

Sleeps 2
1 King Bed

Standard Room, 2 Queen Beds

Good

Highlights

Air conditioning

Connecting rooms available

Free cribs/infant beds

Plasma TV

Renovated in 2023

Frette Italian linens

Blackout drapes/curtains

Pillowtop bed

Sleeps 4
2 Queen Beds

Suite, Non Smoking

Very good

Highlights

Air conditioning

Connecting rooms available

Free cribs/infant beds

Plasma TV

Renovated in 2023

Sofa bed

Blackout drapes/curtains

Premium bedding

Sleeps 6
2 Queen Beds and 1 Double Sofa Bed

Room, 1 King Bed, Accessible, Non Smoking

Very good

Highlights

Air conditioning

Connecting rooms available

Free cribs/infant beds

Plasma TV

Renovated in 2023

Sofa bed

Blackout drapes/curtains

Premium bedding

Sleeps 2
1 King Bed

Room, 2 Queen Beds, Accessible, Non Smoking

Excellent

Highlights

Air conditioning

Connecting rooms available

Free cribs/infant beds

Plasma TV

Renovated in 2023

Sofa bed

Blackout drapes/curtains

Premium bedding

Sleeps 4
2 Queen Beds

Suite, 1 King Bed, Accessible, Non Smoking

Exceptional

Highlights

Air conditioning

Connecting rooms available

Free cribs/infant beds

Plasma TV

Renovated in 2023

Sofa bed

Blackout drapes/curtains

Premium bedding

Sleeps 4
1 King Bed

Suite, Multiple Beds, Accessible, Non Smoking

Wonderful

Highlights

Air conditioning

Connecting rooms available

Free cribs/infant beds

Plasma TV

Renovated in 2023

Sofa bed

Blackout drapes/curtains

Premium bedding

Sleeps 6
2 Queen Beds and 1 Double Sofa Bed

Suite, 1 Queen Bed with Sofa bed, Non Smoking (Non Smoking/Interior Hall)

Highlights

Air conditioning

Connecting rooms available

Free cribs/infant beds

Plasma TV

Renovated in 2023

Frette Italian linens

Blackout drapes/curtains

Pillowtop bed

Sleeps 4
1 Queen Bed and 1 Double Sofa Bed

Suite, 1 King Bed with Sofa bed, Non Smoking (Non Smoking/Interior Hall)

Highlights

Air conditioning

Connecting rooms available

Free cribs/infant beds

Plasma TV

Renovated in 2023

Frette Italian linens

Blackout drapes/curtains

Pillowtop bed

Sleeps 4
1 King Bed and 1 Double Sofa Bed

Suite, 1 King Bed with Sofa bed, Non Smoking (1 Room Suite, No Smkng/Interior Hall)

Highlights

Air conditioning

Connecting rooms available

Free cribs/infant beds

Plasma TV

Renovated in 2023

Frette Italian linens

Blackout drapes/curtains

Pillowtop bed

Sleeps 4
1 King Bed and 1 Double Sofa Bed

Similar properties

Pool
Free breakfast
Pet friendly
Free parking

$98 nightly

Nov 2 - Nov 3

Total with taxes and fees

Earn OneKeyCash on thousands of hotels when you sign in and book. More rewards for more adventures!

Sign in Sign up, it's free

About the neighborhood

221 Britain St, Santee, SC, 29142

What's nearby

Santee Cooper Country Club - 13 min walk - 1.2 km
Santee National Golf Club - 2 min drive - 2.0 km
Santee Town Hall - 3 min drive - 2.0 km
Santee State Park - 4 min drive - 2.3 km
Santee National Wildlife Refuge - 12 min drive - 11.1 km

Getting around

Charleston Intl. Airport (CHS) - 58 min drive

Restaurants

‪McDonald's - ‬4 min walk
‪Bojangles' Famous Chicken 'n Biscuits - ‬11 min walk
‪Starbucks - ‬9 min walk
‪The Lakehouse - ‬7 min drive
‪Cracker Barrel Old Country Store - ‬5 min walk

About this property

Comfort Inn & Suites Santee

Located in the entertainment district, Comfort Inn & Suites Santee is a great choice for a stay in Santee. Guests can take a dip in the seasonal outdoor pool or visit the fitness center for a workout. Fellow travelers love the helpful staff.

At a glance

Hotel size

- 61 rooms
- Arranged over 3 floors

Arriving/Leaving

- Check-in time starts at 3:00 PM
- Check-out time is 11:00 AM

Special check-in instructions

- Front desk staff will greet guests on arrival at the property
- The credit card used to book the reservation must be presented by the cardholder at check-in along with matching photo identification, and other arrangements must be coordinated with the property prior to arrival

Required at check-in

- Credit card, debit card, or cash deposit required for incidental charges
- Government-issued photo ID may be required

Children

- Children (15 years old and younger) stay free when occupying the parent or guardian's room, using existing bedding

Pets

- Pets not allowed
- Service animals welcome

Internet

- Free WiFi in public areas
- Free WiFi in rooms

Parking

- Free onsite self parking
- Wheelchair-accessible parking on site
- Onsite parking limited

Other information

- Designated smoking areas

Property amenities

Food and drink

Free buffet breakfast
Coffee/tea in a common area
Water dispenser

Traveling with children

Children stay free (see details)

Working away

Business center
Computer station

Services

24-hour front desk
Laundry facilities
Free newspapers in lobby
Multilingual staff

Facilities

1 building/tower
Safe-deposit box at front desk
Fireplace in lobby
Television in common areas
Fitness center
Seasonal outdoor pool

Accessibility

Elevator
Elevator door width (inches): 1
Wheelchair-accessible parking
4 on-site accessible parking spaces
Wheelchair-accessible public washroom
Wheelchair-accessible pool

Room amenities

Be entertained

Plasma television
Satellite TV channels

Home comfort

Climate-controlled air conditioning and heating
Coffee/tea maker
Iron/ironing board

Sleep well

Blackout drapes/curtains
Premium bedding
Pillowtop mattress
Free crib/infant bed

Freshen up

Private bathroom
Shower/tub combination
Hair dryer
Towels

Stay connected

Free WiFi
Free local calls

More

Daily housekeeping
Connecting/adjoining rooms available

Fees & policies

Pool, spa, & gym (if applicable)

Pool access available from 10 AM to 10 PM
The seasonal pool is open from March to October

Policies

The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation.

The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation.

This property accepts credit cards. Cash is not accepted.

Credit cards accepted: Visa, Mastercard, American Express, Discover

This property reserves the right to pre-authorize the guest's credit card prior to arrival.

Only bookings from non-local guests are accepted. Guests whose residence is within 20 mi (32 km) of the property will not be allowed to check in.

This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Choice).

Please note that cultural norms and guest policies may differ by country and by property. The policies listed are provided by the property.

Also known as

Comfort Inn Hotel Santee

Comfort Inn Santee

Comfort Inn Santee Hotel

Comfort Inn Suites Santee

Comfort & Suites Santee Santee

Comfort Inn & Suites Santee Hotel

Comfort Inn & Suites Santee Santee

Frequently asked questions

Does Comfort Inn & Suites Santee offer free cancellation for a full refund?

Yes, Comfort Inn & Suites Santee does have fully refundable room rates available to book on our site. If you’ve booked a fully refundable room rate, this can be cancelled up to a few days before check-in depending on the property's cancellation policy. Just make sure to check this property's cancellation policy for the exact terms and conditions.