Photo by Hazem Abdul
3 Star Hotels in South Main
Free cancellation options if plans change
Unlock travel rewards with One Key
Save more with Member Prices
Check prices for these dates
3 Star Hotels in South Main

Wingate Houston near NRG Park/Medical Center
Wingate Houston near NRG Park/Medical Center
6.6 out of 10, (943)
$79 nightly
The price is $92
Oct 11 - Oct 12
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top landmarks in Houston
George R. Brown Convention Center

George R. Brown Convention Center
4/5(961 reviews)
George R. Brown Convention Center is worth a pic or two when discovering Downtown Houston. Our travelers also like the art galleries in the area— your cultural tour starts here.
NASA Johnson Space Center

NASA Johnson Space Center
4.5/5(1,214 reviews)
After visiting NASA Johnson Space Center, make a plan to see the other sights and activities in Houston. Amble around the area's lakeside or attend a sporting event.
Check out reviews of South Main hotels guests love

DoubleTree by Hilton Hotel Houston - Greenway Plaza
10/10 Excellent
Keep exploring
- Heaker Hotels
- 2 Star Hotels in Richmond Avenue
- 3 Star Hotels in Richmond Avenue
- 4 Star Hotels in Richmond Avenue
- 5 Star Hotels in Richmond Avenue
- Hotels near James Turrell's Twilight Epiphany Skyscape
- Hotels near Sculpture Park
- Hotels near Main Street Theater - Rice Village
- Hotels near Reckling Park
- Hotels near Texas Children's Hospital
- Hotels near NRG Center
- Hotels near Houston Methodist Hospital
- Hotels near NRG Stadium
- Hotels near NRG Arena
- Central Southwest Hotels
- 3 Star Hotels in Braeswood Place
- 2 Star Hotels in Sharpstown
- 2 Star Hotels in Greater Hobby Area
- Willow Meadows/Willowbend Area Hotels
- Hotels near Houston Sports Park
- Hotels near UT Health Science Center
- Hotels near Menninger Clinic Campus
- Hotels near Kelsey Seybold
- Hotels near Lakewood Church
- Hotels with Kitchens in Houston
- Pet Friendly Hotels in Houston
- Cheap Hotels in Houston
- Luxury Hotels in Houston
- 1 Star Hotels in Houston
- 2 Star Hotels in Houston
- 3 Star Hotels in Houston
- 4 Star Hotels in Houston
- 5 Star Hotels in Houston
- Houston Hotels
- Hotels near William P. Hobby
- Hotels near George Bush Intercontinental
- Bellaire Hotels
- Hotels near Houston Museum of Fine Arts
- Hotels near Houston Zoo
- Hotels near Houston Natural Science Museum
- Hotels near Toyota Center
- Galveston Hotels
- Hotels near Hermann Park
- Hotels near Miller Outdoor Theater
- Hotels near Rice Stadium
- Hotels near Wildcat Golf Club
- Houston Museum District Hotels
- Hotels near Dryden/TMC Station
- Hotels near Fannin South Station
- Hotels near Hermann Park/Rice U Station
- Hotels near Memorial Hermann Hospital/Houston Zoo Station
- Hotels near Stadium Park/Astrodome Station
- Hotels near TMC Transit Center
- 2 Star Hotels in Buffalo Bayou Park
- 3 Star Hotels in Buffalo Bayou Park
- 4 Star Hotels in Buffalo Bayou Park
- Hotels near Nature Discovery Center
- 4 Star Hotels in Harwin Drive Shopping District
- 5 Star Hotels in Harwin Drive Shopping District
- Hotels near Meyerland Plaza Shopping Center
- Hotels near MD Anderson Cancer Center
- Hotels near NRG Park
- Hotels near Rice University
- Hotels near Daikin Park
- Hotels near The Woman's Hospital of Texas
- Hotels near Chi St. Lukes Health Baylor College Of Medicine Medical Center
- Hotels near Shriners Hospitals For Children
- Hotels near Memorial Hermann Hospital
- Hotels near Harris Health System - Ben Taub General Hospital
- Hotels near Woman Hospital Of Texas Clinical
- Hotels near Woman's Hospital of Texas
- Hotels near HCA Houston Healthcare Medical Center
- Hotels near Harris Health System
- Hotels near Baylor St. Luke's Medical Center-McNair Campus
- Hotels near CHI St. Luke's Health-Baylor St. Luke's Medical Center
- Hotels near American Cowboy Museum
- Hotels near Aveva Stadium
- Hotels near Tudor Fieldhouse
- Hotels near Kinder Station
- Hotels near NRG Astrodome
- Hotels near George R. Brown Convention Center
- 3 Star Hotels in Montrose
- Montrose Hotels
- University Place Hotels
- Family Hotels in Braeswood Place
- Braeswood Place Hotels
- Astrodome Hotels
- Southampton Hotels
- Southgate Hotels
- The Galleria Hotels
- Downtown Houston Hotels
- 3 Star Hotels in East Downtown Houston
- Riverside Terrace Hotels
- Hotels near Greenway Plaza
- 2 Star Hotels in Memorial
- 3 Star Hotels in Memorial
- West University Place Hotels
- Southside Place Hotels
- Texas Medical Center Hotels
- Southwest Houston Hotels