Hotels in Upstate South Carolina

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Grand Bohemian Lodge Greenville, Autograph Collection

4.0 star property
9.6 out of 10, Exceptional, (361)
The price is NT$7,113
NT$7,824 total
includes taxes & fees
Aug 17 - Aug 18
Grand Bohemian Lodge Greenville, Autograph Collection

Hampton Inn & Suites Greenville Airport, SC

2.5 star property
9.2 out of 10, Wonderful, (918)
The price is NT$2,973
NT$3,270 total
includes taxes & fees
Aug 15 - Aug 16
Hampton Inn & Suites Greenville Airport, SC

SpringHill Suites by Marriott Greenville Downtown

2.5 star property
9.6 out of 10, Exceptional, (1007)
The price is NT$3,268
NT$3,595 total
includes taxes & fees
Aug 17 - Aug 18
SpringHill Suites by Marriott Greenville Downtown

Hampton Inn & Suites Greenville-Downtown-RiverPlace

2.5 star property
9.4 out of 10, Exceptional, (1009)
The price is NT$3,739
NT$4,236 total
includes taxes & fees
Aug 14 - Aug 15
Hampton Inn & Suites Greenville-Downtown-RiverPlace

Hotel Hartness

4.0 star property
9.8 out of 10, Exceptional, (559)
The price is NT$5,028
NT$6,526 total
includes taxes & fees
Jul 27 - Jul 28
Hotel Hartness

Days Inn by Wyndham Clinton / Laurens I-26

2.0 star property
6.6 out of 10, (380)
The price is NT$1,746
NT$1,903 total
includes taxes & fees
Aug 3 - Aug 4
Days Inn by Wyndham Clinton / Laurens I-26

Courtyard by Marriott Greenville Downtown

3.0 star property
9.4 out of 10, Exceptional, (1000)
The price is NT$3,268
NT$3,595 total
includes taxes & fees
Aug 17 - Aug 18
Courtyard by Marriott Greenville Downtown

Best Western Plus Greenville I-385 Inn & Suites

2.5 star property
9.2 out of 10, Wonderful, (1343)
The price is NT$2,486
NT$2,735 total
includes taxes & fees
Jul 27 - Jul 28
Best Western Plus Greenville I-385 Inn & Suites

Hyatt Place Greenville Downtown

3.0 star property
9.2 out of 10, Wonderful, (1004)
The price is NT$3,722
NT$4,217 total
includes taxes & fees
Jul 27 - Jul 28
Hyatt Place Greenville Downtown

Mint House Greenville - Downtown

4.0 star property
9.2 out of 10, Wonderful, (693)
The price is NT$3,148
NT$3,557 total
includes taxes & fees
Aug 17 - Aug 18
Mint House Greenville - Downtown

Holiday Inn Express Gaffney by IHG

2.5 star property
8.6 out of 10, Excellent, (339)
The price is NT$2,293
NT$2,499 total
includes taxes & fees
Jul 27 - Jul 28
Holiday Inn Express Gaffney by IHG

Comfort Inn & Suites Greer - Greenville

2.5 star property
8.6 out of 10, Excellent, (648)
The price is NT$3,016
NT$3,287 total
includes taxes & fees
Jul 27 - Jul 28
Comfort Inn & Suites Greer - Greenville

Fairfield Inn & Suites Seneca Clemson Univ Area

2.5 star property
9.4 out of 10, Exceptional, (175)
The price is NT$3,791
NT$4,171 total
includes taxes & fees
Jul 22 - Jul 23
Fairfield Inn & Suites Seneca Clemson Univ Area

Best Western Plus Greenville South

2.5 star property
8.2 out of 10, Very Good, (629)
The price is NT$2,973
NT$3,300 total
includes taxes & fees
Jul 27 - Jul 28
Best Western Plus Greenville South

Holiday Inn Express & Suites Greenville Airport by IHG

3.5 star property
8.0 out of 10, Very Good, (774)
The price is NT$3,674
NT$4,041 total
includes taxes & fees
Jul 26 - Jul 27
Holiday Inn Express & Suites Greenville Airport by IHG

Hampton Inn Anderson/ Alliance Business Park

2.5 star property
9.2 out of 10, Wonderful, (768)
The price is NT$3,374
NT$3,746 total
includes taxes & fees
Jul 27 - Jul 28
Hampton Inn Anderson/ Alliance Business Park

Aloft Greenville Downtown

3.0 star property
9.0 out of 10, Wonderful, (1007)
The price is NT$3,682
NT$4,050 total
includes taxes & fees
Jul 27 - Jul 28
Aloft Greenville Downtown

The Inn at Patrick Square

3.5 star property
9.8 out of 10, Exceptional, (734)
The price is NT$4,206
NT$4,669 total
includes taxes & fees
Jul 22 - Jul 23
The Inn at Patrick Square

Woodspring Suites Greenville Airport

2.5 star property
8.6 out of 10, Excellent, (114)
The price is NT$2,116
NT$2,328 total
includes taxes & fees
Jul 22 - Jul 23
Woodspring Suites Greenville Airport

ECHO Suites Extended Stay by Wyndham Spartanburg

2.0 star property
8.0 out of 10, Very Good, (181)
The price is NT$2,764
NT$3,068 total
includes taxes & fees
Jul 23 - Jul 24
ECHO Suites Extended Stay by Wyndham Spartanburg
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Upstate South Carolina, SC

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Top landmarks in Upstate South Carolina

Learn more about Upstate South Carolina

Upstate South Carolina is well-known for its university life and sports, featuring attractions such as Discovery Island Water Park and Frankie's Fun Park. This family-friendly city has something for everyone including its live music, restaurants, and sights like The Shops at Greenridge and Conestee Nature Preserve.

Greenville - Spartanburg showing a sunset, tranquil scenes and mountains
Photo by South Carolina Department of Parks, Recreation & Tourism
Open Photo by South Carolina Department of Parks, Recreation & Tourism

Check out reviews of Upstate South Carolina hotels guests love

Frequently asked questions

Can I book refundable accommodations in Upstate South Carolina?
If you're looking for the flexibility to change your plans to Upstate South Carolina, most accommodations provide refundable* rates you can book. You can see these properties by searching our site and using the "fully refundable" filter to narrow the results down.
Where can I stay in Upstate South Carolina if I want a vacation rental instead of a hotel?
If you want to find a good alternative to a hotel, browse our selection of 1070 vacation homes. In addition, there are 113 apartments and 89 condos.
Why should I book my Upstate South Carolina hotel through Hotels.com?
There are lots of reasons to book your Upstate South Carolina trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.