5 Star Hotels in Panama City

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5 Star Hotels in Panama City

Popular Panama City 5-star hotels to try out

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top neighborhoods in Panama City

Casco Viejo

Casco Viejo's cobblestone streets tell Panama's colonial story at every turn. The golden Metropolitan Cathedral and historic theaters create a living museum vibe. Rooftop bars offer spectacular bay views while museums showcase Panama's diverse heritage. Plaza hopping rewards you with hidden architectural gems and cultural performances that bring history to life. The neighborhood serves up everything from fusion cuisine in restored mansions to traditional Panamanian dishes. Boutique hotels occupy colonial buildings with charming courtyards and personalized service. Though compact, comfortable walking shoes are essential for navigating the uneven historic streets.

Bella Vista

Bella Vista balances Panama City's sleek business side with upscale urban living. Gleaming skyscrapers along Avenida Balboa house financial headquarters while trendy spots on Calle Uruguay buzz with after-work crowds. Shop at MultiPlaza Pacific mall, visit Crown Casino, or simply stroll the waterfront promenade for stunning bay views. Getting around is a breeze with two metro stations and plentiful taxis. Dining options range from rooftop restaurants to international cuisine that won't disappoint. High-rise hotels with spectacular views cater to business travelers and tourists who appreciate modern comforts with a side of ocean breeze.

El Cangrejo

El Cangrejo pulses with modern energy around the iconic "El Tornillo" tower, where art meets business in Panama City's cosmopolitan heart. Korean BBQ aromas mingle with coffee scents from sidewalk cafes, while galleries showcase local talent beneath tropical sunshine. Colorful murals splash across office buildings as diverse cultures blend in this trendy district. The neighborhood serves up an eclectic fusion of Korean, Jewish, and Panamanian cuisines in stylish eateries and casual cafes. Modern boutique hotels and upscale business lodging dominate accommodation options. Getting around is a breeze with nearby Metro Line 1 stations, abundant taxis, and pleasantly walkable streets.

Obarrio

Obarrio dazzles with gleaming skyscrapers housing Panama City's financial powerhouses and luxury shopping. Multiplaza Pacific mall tempts with designer boutiques while the business crowd buzzes between meetings. When you're not trying your luck at local casinos, relax at a sophisticated coffeehouse or stroll the wide, clean sidewalks of Calle 50. Hotels range from international chains to boutique properties, with rates reflecting the upscale surroundings. Getting around is a breeze with excellent taxi service, frequent buses along Via España, and the Metro Line 1 connecting directly to Iglesia del Carmen station.

Punta Pacifica

Punta Pacifica's gleaming glass towers and an iconic sail-shaped skyscraper create a skyline that screams luxury with a Pacific Ocean backdrop. Stroll the waterfront promenades where swaying palms frame perfect sunset views, or duck into Multiplaza Pacific Mall to browse designer boutiques in marble-floored splendor. The neighborhood balances business and pleasure with its mix of corporate offices and upscale leisure spots. Dining here means international cuisine with ocean views at rooftop bars and hotel restaurants where reservations are smart moves. High-rise hotels and serviced apartments offer amenities like infinity pools and concierge services. Getting around is easy with abundant taxis and walkable streets, though you won't find much public transit in this polished enclave.

Top landmarks in Panama City

Find out more about 5 Star Hotels in Panama City

Find out more about 5 Star Hotels in Panama City

What can I expect from 5-star hotels in Panama City?

When you stay at 5-star hotels in Panama City during 2025, you can expect exceptional service, luxurious rooms, and all the high-end amenities you could possibly want from your stay. From the moment you arrive, you'll feel like a VIP. The attentive service and exceptional hospitality of the hotel staff and concierge will take care of your every need, whether it's round-the-clock room service, childcare, or a reservation at one of Panama City's top restaurants. Then there are the rooms. A 5-star hotel in Panama City typically includes opulent furnishings, personalized welcome kits, and premium bedding. Remember, the search filters on Hotels.com help you find specific amenities or extras you're seeking.

What makes the best 5-star hotels in Panama City stand out?

Some of the best 5-star hotels in Panama City stand out for their distinct features and extras, often inspired by local traditions and culture. These add a touch of authenticity to your stay. Panama City's most high-end properties typically boast several on-site restaurants serving up extraordinary fusion dishes showcasing the local cuisine in elegant settings. Some of the most popular luxury hotels in Panama City include special extras in their rooms and suites, too. Think hot tubs, exceptional views, and the latest technology. The detailed and up-to-date property descriptions on Hotels.com explain what you can expect, while verified reviews give you real-life insights into what the guest experience is like.

How much does a 5-star hotel in Panama City typically cost?

In 2025, the cost of five-star hotels in Panama City varies and depends on factors like the time of year and room type. To get a feel for average prices, take advantage of the Hotels.com search wizard. Simply enter your dates and destination to view real-time rates for luxury properties in Panama City.

Are there special deals or discounts for 5-star hotels in Panama City?

Yes, on Hotels.com you'll find some of the best deals and biggest discounts for five-star hotels in Panama City. As one of the world's largest websites for hotel bookings, we're able to negotiate exceptional deals, and we then pass the savings on to you. Then there's One KeyOpens in a new window—Hotels.com's generous reward program. Members can access instant discounts on thousands of hotels simply by signing in. Keep a look out for the blue savings label in the search results. One Key rewards you with OneKeyCash for most stays, too. You can then use this reward currency to save on future bookings. Plus, as you move up the tier levels, you'll unlock special perks, such as VIP Access to select hotels, free room upgrades, and even early check-in. Best of all, One Key is free to join. As if all that wasn't enough, you can save on 5-star hotels in Panama City by searching and booking through the Hotels.com app. 

How can I verify if a hotel in Panama City is rated 5 stars?

There are two really easy ways to confirm if a Panama City hotel is five stars on Hotels.com. You can check the “5-star rating” filter to view a list of all properties rated as 5 stars in Panama City. Or you can look for the star rating above the property name on the hotel's dedicated page. Hotels.com keeps all its descriptions up to date, so you can feel confident that what you see is what you book.

Do Panama City 5-star hotels offer free cancellation options?

Yes, Panama City 5-star hotels booked through Hotels.com usually come with free cancellation. This means you can change your mind as much as you like when booking on Hotels.com. Just keep in mind that each property has different booking conditions, though. It's always a good idea to glance over these before confirming your stay. The good news is that all this information is easy to find on Hotels.com—just look out for the “free cancellation” label or use the “fully refundable” filter when searching.

What amenities do 5-star hotels in Panama City provide?

Most 5-star hotels in Panama City boast high-end amenities like luxury spas and several upscale restaurants. Stay at one of these opulent properties if you're seeking full-body massages, holistic treatments, and rejuvenating therapies. When it comes to dining, you can expect exquisite cuisine prepared by some of Panama City's best chefs. More luxury amenities include elegant bars serving signature cocktails prepared by expert mixologists, state-of-the-art fitness centers, and even yoga classes.

Are there family-friendly 5-star hotels in Panama City?

The “family-friendly” search filter will reveal all the 5-star hotels in Panama City that will welcome you and your little ones with open arms. Kid-friendly 5-star hotels typically feature all you need for a relaxing stay, including children's facilities like shallow-water pools, changing facilities, and even dedicated day-care facilities with an expertly trained staff member. You'll also often find luxurious family suites and interconnecting rooms, as well as cribs and special beds for children.

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