Hotels in Santa Isabel

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

How much does a hotel room cost in Santa Isabel?
You can choose a great hotel in Santa Isabel from $47 with properties to suit all budgets and needs. If you're after an affordable hotel in Santa Isabel that meets all of your requirements, set your filters and then sort the results by "Price: low to high". If you're a member, don't forget to sign in to your account to unlock more savings.
How can I find deals and earn rewards at Santa Isabel hotels?
Members can save up to 20% on select hotels in Santa Isabel. Plus, Silver, Gold and Platinum members earn extra rewards on VIP Access bookings, making each stay even more rewarding.

Can I book Santa Isabel hotels with free cancellation?
It's easy to book a refundable Santa Isabel hotel on Hotels.com. Simply filter hotels by "Property cancellation options" and select "Fully refundable property". Most hotels offer free cancellation, so you can receive a refund if you need to cancel. Some hotels do require cancelling more than 24 hours before check-in, so double-check your booking beforehand.
What are some popular hotels in central Santa Isabel?
If you're looking for hotels in central Santa Isabel, check out Hotel del Norte and Desert Inn Mexicali. Travelers love Hotel del Norte for its location, as well as the restaurant, bar/lounge and coffee shop/cafe this hotel offers. Desert Inn Mexicali is another popular central hotel with 2 outdoor pools, a free continental breakfast and free parking. Mexicali Historic Center is a central neighborhood for your Santa Isabel vacation.
Are all taxes and fees included in the Santa Isabel hotel prices shown on Hotels.com?
Hotels.com provides upfront pricing so you can relax knowing you won't be met with surprise additional fees or taxes when you're ready to confirm your booking. From the time you start your search on Hotels.com, the price you see is what you pay. This makes it much easier to compare properties and secure our best deal for your next getaway.
What hotels do travelers recommend in Santa Isabel?
Can I book a refundable hotel in Santa Isabel?
If you need the flexibility to change your plans to Santa Isabel, most properties provide refundable* bookable rates. You can see these properties by searching our site and using the "fully refundable" filter to narrow the results down.
What will the weather in Santa Isabel be like during my trip?
July and August are typically the warmest months in Santa Isabel when the average temp is 93°F. December and January are the coldest months when the average temperature is 61°F. August and January are the months with the most rain.
Why should I book my Santa Isabel hotel through Hotels.com?
There are lots of reasons to book your Santa Isabel trip with us: our free cancellations on selected hotels gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™* on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Find out more about Santa Isabel

Find out more about Santa Isabel

Santa Isabel: Where Modernity Meets Enchantment Amidst Nature’s Embrace

Nestled in the heart of Mexicali, Santa Isabel is a hidden gem that perfectly blends modern charm with cultural richness. Known for its inviting atmosphere and warm Cuban hospitality, this quaint town offers travelers a unique escape. Explore the picturesque landscapes, where the arid beauty of Baja California meets vibrant local life. Key attractions include the impressive civic government building, showcasing contemporary architecture, and the surrounding natural wonders perfect for outdoor enthusiasts. With its off-the-beaten-path allure, Santa Isabel promises an authentic experience filled with local flavors and unforgettable memories, making it a must-visit destination for adventurous souls.

Discover great hotels in Santa Isabel

Santa Isabel in Mexicali offers a range of accommodations, from stylish hotels to superior options for a luxurious stay. You'll find comfortable rooms and quality amenities that cater to both relaxation and convenience, making it a great spot for travelers seeking an enjoyable getaway. Here are some of our travelers' favorite hotels in Santa Isabel:

  1. OYO Hotel Don JuanOpens in a new window: OYO Hotel Don Juan is a cozy 2.0-star hotel designed for travelers seeking comfort without frills. This property offers essential amenities such as a television for entertainment, ensuring a relaxing stay. The inviting atmosphere makes it a great choice for leisure travelers who prioritize simplicity and accessibility. Positive reviews highlight the hotel’s welcoming environment and the ease of settling in after a day of exploration, making it a solid option for those looking to unwind in a straightforward setting.
  2. Hotel del NorteOpens in a new window: Hotel del Norte is a stylish 3.0-star hotel located in the heart of the city, perfect for business travelers seeking a vibrant urban experience. This property features a range of business amenities, including a 24-hour business center and meeting rooms, catering to professionals on the go. The hotel's modern design and city-themed decor create an inspiring environment for work and relaxation. Reviewers appreciate the hotel's commitment to inclusivity and the convenience of its location, making it a preferred choice for those looking to blend work and leisure seamlessly.
  3. Hotel Frontera BajaOpens in a new window: Hotel Frontera Baja offers a comfortable 2.0-star setting, tailored specifically for business travelers. This hotel combines functionality with a warm ambiance, ensuring a productive stay. Essential business services and facilities enhance the overall experience, allowing guests to focus on their work while enjoying a relaxed atmosphere. Positive sentiments from past visitors emphasize the hotel's ability to provide a supportive environment for work-related endeavors, making it a notable choice for those traveling for business purposes.

Top locations to stay in Santa Isabel

Some of the best areas to stay in Santa Isabel, Mexicali, Baja California, Mexico, are Mexicali, Calafia, and the Civic Center. Mexicali offers vibrant nightlife and cultural experiences, while Calafia boasts beautiful points of interest and natural beauty. The Civic Center is ideal for those interested in desert landscapes and local events. For first-time visitors, Mexicali is the most appealing choice.

  1. MexicaliOpens in a new window: Mexicali is a vibrant city known for its rich cultural scene and energetic atmosphere. With a strong affinity for dancing and lively music, you’ll find plenty of opportunities to experience local traditions and enjoy festive events. The city is also a shopping haven, offering a mix of bustling markets and modern malls where you can find unique souvenirs and local crafts. Plus, the diverse culinary scene will delight your taste buds with delicious street food and authentic Mexican cuisine. Don’t miss the chance to explore the nearby desert landscapes, perfect for those who appreciate nature and scenic views.
  2. CalafiaOpens in a new window: Calafia is a charming area that beautifully blends relaxation and recreation. It’s known for its picturesque surroundings and outdoor activities, making it an ideal spot for those seeking a peaceful getaway. The area boasts stunning landscapes perfect for light hiking and exploration. Additionally, the local culture is rich, with opportunities to enjoy traditional dances and festivals that showcase the region’s heritage. The laid-back vibe of Calafia makes it a great place to unwind while still being close to the vibrant energy of Mexicali.
  3. Civic CenterOpens in a new window: The Civic Center is the heart of Mexicali’s cultural life, where you can immerse yourself in the local community. It features various cultural attractions, including museums and galleries that highlight the area’s history and artistic talent. The surrounding parks offer a peaceful escape within the city, ideal for a leisurely stroll or a picnic. The Civic Center is also a great spot for attending cultural events and festivals, ensuring you get a taste of the local spirit. Its central location makes it easy to access other attractions across Mexicali.

Things to do in Santa Isabel

Santa Isabel offers a stunning blend of sandy beaches, lush mountains, and serene parks, making it an outdoor lover's paradise. Travelers can enjoy sun-soaked days by the water, hike through verdant trails, or relax in tranquil green spaces. Its vibrant natural landscapes promise unforgettable experiences for everyone.

  • Mexicali Border Port IOpens in a new window – Begin your adventure at Mexicali Border Port I, a modern civic building that serves as a key gateway between the United States and Mexico. This bustling port is not only functional but also a vibrant place where you can observe the flow of people and goods, setting the stage for your explorations in Mexicali.
  • Plaza de Toros CalafiaOpens in a new window – Step into the rich cultural heritage of the region at Plaza de Toros Calafia. This historic bullring offers a glimpse into traditional Mexican festivities, showcasing the colorful atmosphere of bullfighting events. Even if you don’t catch a show, the architecture and ambiance are worth experiencing.
  • State Center for the Arts (CEART)Opens in a new window – Discover a diverse array of artistic expressions at the State Center for the Arts (CEART). This dynamic arts center hosts exhibitions, performances, and workshops, making it a hub for creativity. Engage with local artists and enjoy the vibrant cultural scene that reflects the spirit of Baja California.
  • House of CultureOpens in a new window – Conclude your exploration at the House of Culture, a museum that celebrates the artistic and historical narratives of the region. Here, you can delve into exhibits that highlight local traditions, crafts, and the rich tapestry of Mexicali's past, providing a deeper understanding of the area's cultural landscape.

5 tips for savvy savings when booking a hotel in Santa Isabel

  1. Book for the cheapest times: The most budget-friendly time to visit Santa Isabel is during August, September, and December, when hotel prices tend to be lower. For a great value for money experience, it's recommended to stay for at least 2 to 3 days to fully explore the area's significant landmarks and cultural sites. During your visit, you can enjoy attractions like a local winery, scenic vineyards, and a modern civic government building that reflects the region's history and culture. By planning your trip during these months, you could benefit from even more affordable options, as prices may drop.
  2. Look for last-minute deals on Hotels.com: To discover last-minute deals to Santa Isabel, check the DealsOpens in a new window or Last-Minute DealsOpens in a new window sections on Hotels.com, where you may find discounted hotel rates as your travel date approaches. Consider enabling email alerts or push notifications to stay updated on flash sales and special promotions. This way, you're more likely to catch great savings. Additionally, use Smart ShoppingOpens in a new window the app's comparison tool, to help you compare hotel prices and amenities effectively. If room availability changes or prices drop, you’ll be among the first to know, making it easier to book your last-minute getaway.
  3. Be flexible with dates: Prices can fluctuate based on factors like the hotel’s location, star rating, and the time of year, so being flexible with your travel dates might help you save on your stay at the Santa Isabel hotel. If you’re seeking a unique experience, boutique hotels can provide a more personalized touch and sometimes offer better value. When you book through Hotels.com, we’ll inform you if the price for your chosen dates is above or below the average. If the price is on the higher side, we’ll suggest alternative dates that could be more affordable, increasing your chances of getting a great deal.
  4. Consider your location: Staying near major attractions or city centers can be convenient, but it often comes with higher prices. For more affordable options, you might want to look at hotels located in less central areas or neighborhoods, striking a balance between cost and accessibility to your desired destinations. You could also consider independent hotels a bit further out, which can offer a more genuine and budget-friendly experience.
  5. Become a Member: Join our membership for free and unlock amazing savings on your next stay in Santa Isabel! Enjoy exclusive member prices on over 100,000 hotels worldwide. As you progress through our membership tiers, you’ll gain access to fantastic perks, including complimentary room upgrades (when available) and discounts on food and beverages at select VIP Access properties. Start your journey to a more rewarding travel experience today!

If you're looking to discover somewhere new, look no further than Santa Isabel. Whether you're planning to stay for a night or for the week, the area around Santa Isabel has accommodations to fit every need. Search for hotels in Santa Isabel with Hotels.com by checking our online map. Our map displays the areas and neighborhoods around all Santa Isabel hotels so you can see how close you are from landmarks and attractions, and then refine your search within the larger area. The best Santa Isabel hotel deals are here with our lowest price guarantee.

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