The staff at Ca' Vendramin Zago are very friendly, helpful, and made me feel welcome.
Ca' Vendramin Zago traces its history to the 16th century. I stayed in a small suite with a balcony and a canal view. My room had a high ceiling with a fresco and a chandelier made from Murano glass. It is this sense of history that I enjoyed most about the room.
Overall the room was clean and functional, but it was not without a few downsides. The bathroom was tiny and there were a few small items that did not quite work (an inoperative motion sensor light, shower door that closed only with difficulty, a hallway door that scraped on the floor).
I found the hotel location to be quite convenient. Less than 100m from a main thoroughfare, and perhaps a 6 minute walk from a vaporetto (water bus) dock.