Business Hotels in San Francisco

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Business Hotels in San Francisco

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top neighborhoods in San Francisco

Fisherman's Wharf

Fisherman's Wharf dazzles with classic San Francisco sights and sounds that'll make your camera work overtime. Sea lions bark and sunbathe at Pier 39 while street performers turn sidewalks into stages. The Aquarium of the Bay lets you walk under sharks, and historic ships at Hyde Street Pier whisper tales of maritime adventures. Grab a steaming sourdough bowl of clam chowder or fresh Dungeness crab from waterfront eateries that range from casual to upscale. Hotels with bay views provide perfect crash pads after long days of exploration. Getting around is simple with multiple bus lines, the iconic cable car terminus, and wide pedestrian areas perfect for strolling.

Nob Hill

Perched atop one of San Francisco's famous hills, Nob Hill flaunts its old-money swagger with grand hotels and Gothic architecture. Grace Cathedral's spires reach skyward while cable cars rattle past mansions that seem frozen in time. You can spend hours exploring the Cable Car Museum or wandering through Huntington Park's manicured gardens with their ornate fountains and spectacular city views. Hotel bars serve craft cocktails alongside piano melodies, and upscale restaurants offer white-tablecloth dining experiences. Getting around is a breeze with three metro stops and those iconic cable cars connecting you to downtown and Chinatown. The steep streets might leave you breathless, but the panoramic vistas make every climb worth it.

Union Square

Union Square delivers San Francisco's most electric shopping scene, where luxury flagships and department stores surround a bustling central plaza. Street performers entertain beside the towering Dewey Monument while theater marquees promise evening shows. Cable cars clang past historic hotels and designer boutiques, creating a vibrant urban energy that feels distinctly San Francisco. Getting around couldn't be easier with the Powell Street cable car terminus and nearby metro stops connecting you everywhere. Upscale hotel restaurants and rooftop lounges dominate the dining scene. Choose between luxury historic hotels or boutique properties for your stay, all within steps of world-class shopping and entertainment.

Mission District

The Mission District pulses with colorful murals that tell stories of Latino heritage and artistic rebellion. On weekends, locals sprawl across Dolores Park with skyline views and picnic spreads. Wander down 24th Street to discover authentic taquerias, quirky boutiques, and the historic Mission Dolores, San Francisco's oldest building. Getting around is a breeze with two BART stations and several bus lines connecting you to downtown. Hip cafes and lively bars along Valencia Street make perfect spots for people-watching, while the neighborhood's mix of Victorian homes and street art creates a vibe that's both gritty and charming.

South of Market

SoMa packs San Francisco's artistic spirit into a neighborhood that's constantly reinventing itself. Converted warehouses now house cutting-edge galleries while SFMOMA's towering glass facade invites you to explore world-class contemporary art. Oracle Park brings baseball energy to the bay, and Yerba Buena Gardens offers a peaceful green escape from the urban buzz. Getting around couldn't be easier with Yerba Buena-Moscone Station and several other transit stops connecting you to the entire city. The restaurant scene ranges from food trucks to upscale dining in industrial-chic spaces. Most visitors stay in modern hotels or boutique properties housed in historic buildings with architectural character.

Top landmarks in San Francisco

Frequently asked questions

What are the best business hotels in San Francisco?
One of the best business hotels in San Francisco according to guests is Hotel Drisco. Make the most of a 24-hour front desk and daily housekeeping services here. Omni San Francisco Hotel is also rated highly by frequent business travelers.
What are the cheapest business hotels in San Francisco?
It's easy to find some of the cheapest San Francisco business hotels from $119 for your next work trip. Keep your travel costs in check at Hampton Inn San Francisco Airport, which offers a conference space and windsurfing. Hampton Inn San Francisco-Daly City is another option that offers great value for traveling professionals.
What is the best time to stay in a business hotel in San Francisco?
September is the warmest month, with temperatures ranging from 59ºF (15ºC) to 77ºF (25ºC). If you like cooler weather, plan your work trip for December. It's generally between 48ºF (9ºC) and 57ºF (14ºC) then. February is the ideal month to escape the crowds and potentially lock in cheaper business hotels in San Francisco.
What business hotels in San Francisco have a pool?
Mansion on Sutter is a top San Francisco business hotel with a pool. Plus, you'll have access to pillow top mattresses and hypo-allergenic bedding during your visit. For more options where you can mix productivity with relaxation, look up The St. Regis San Francisco.
What are the closest business hotels to San Francisco Intl. Airport (SFO)?
About 1 mile southwest of San Francisco Intl. Airport (SFO), Grand Hyatt at SFO is perfect for busy professionals. Make the most of a cafe and hypo-allergenic bedding. Aloft San Francisco Airport is another stay that makes it easy to hop off the plane and into your next meeting. Stay on top of your schedule when you choose a business hotel in San Francisco close to the airport.
What are the best 5-star business hotels in San Francisco?
Hotel Drisco promises sophisticated surroundings for your next meeting with clients. This 5-star San Francisco business hotel features complimentary use of a nearby fitness center and designer toiletries. Alternatively, take your work trip to the next level at Fairmont Heritage Place, Ghirardelli Square.
Are there any business hotels in San Francisco with parking?
Take the stress out of business travel by staying at Omni San Francisco Hotel. This property comes with parking, windsurfing and a bar. Fairmont Heritage Place, Ghirardelli Square is another stay that includes a spot to leave your ride. If you're looking for alternatives, check out the 1,995 San Francisco business hotels with parking.
Are all taxes and fees included in the San Francisco hotel prices shown on Hotels.com?
Hotels.com provide upfront pricing so you can relax knowing you won't be met with surprise additional fees or taxes when you're ready to confirm your booking. From the time you start your search on Hotels.com, the price you see is what you pay. This makes it much easier to compare properties and secure our best deal for your next getaway.

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