Hotels in Mesquite

Free cancellation options if plans change
Unlock travel rewards with One Key
Save more with Member Prices

Check prices for these dates

Tonight
Feb 25 - Feb 26
Tomorrow
Feb 26 - Feb 27
This weekend
Feb 28 - Mar 2
Next weekend
Mar 7 - Mar 9

Where to stay in Mesquite?

Comfort Suites University Las Cruces
Lobby

Comfort Suites University Las Cruces

2.5 star property
8.0 out of 10, Very Good, (999)
The price is $98
includes taxes & fees
$85 per night
Mar 9 - Mar 10
Comfort Suites University Las Cruces
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Mesquite

Mesquite is well-known for its attractions such as Organ Mountains Desert Peaks National Monument and Rio Grande.

See all hotels in Mesquite

Frequently asked questions

What accommodations do travelers like in Mesquite?
Guests like Ramada Hotel & Conference Center by Wyndham Las Cruces, Comfort Suites University Las Cruces and Best Western Mission Inn.
Can I book refundable accommodations in Mesquite?
If you need the flexibility to change your plans to Mesquite, most hotels provide refundable* bookable rates. You can see these accommodations by searching our site and using the “fully refundable” filter to narrow the results down.
What will the weather in Mesquite be like during my trip?
June and July are typically the warmest months in Mesquite when the average temp is 82°F. January and December are the coldest months when the average temperature is 48°F. August and September are the months with the most rain.
Why should I book my Mesquite hotel with Hotels.com?
There are lots of reasons to book your Mesquite trip with us: our free cancellations on selected hotels* gives you flexibility, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.